Use of Celebrex (Celecoxib)

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For safe and effective use of Celebrex (Celecoxib), do not take more of it, do not take it more often, and do not take it for a longer time than ordered by your health care professional. Taking too much of Celebrex (Celecoxib) may increase the chance of unwanted effects.

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Dose of side Celebrex (Celecoxib)

The dose of Celebrex (Celecoxib)will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of Celebrex (Celecoxib). If your dose is different, do not change it unless your doctor tells you to do so.

The number of capsules that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are taking Celebrex (Celecoxib).

For oral dosage form (capsules) of Celebrex (Celecoxib):

  • For familial adenomatous polyposis (polyps in the intestines):
    Adults: 400 mg twice a day with food.
    Children: Use and dose must be determined by your doctor.
  • For moderate or severe pain, such as after dental or orthopedic procedures:
    Adults: On the first day take 400 mg for the first dose then 200 mg as needed as a second dose. After the first day take 200 mg twice a day.
    Children: Use and dose must be determined by your doctor.
  • Pain during menstruation:
    Adults: On the first day take 400 mg for the first dose then 200 mg as needed as a second dose. After the first day take 200 mg twice a day.
    Children: Use and dose must be determined by your doctor.
  • For rheumatoid arthritis:
    Adults: 100 to 200 mg twice a day.
    Children: Use and dose must be determined by your doctor.
  • For osteoarthritis:
    Adults: 200 mg a day as a single dose or 100 mg twice day.
    Children: Use and dose must be determined by your doctor.

Missed dose:

If your health care professional has ordered you to take Celebrex (Celecoxib) according to a regular schedule, and you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the next dose and go back to your regular dosing schedule. Do not double doses.

Storage of Celebrex (Celecoxib):

Keep Celebrex (Celecoxib) out of the reach of children.
Do not store Celebrex (Celecoxib) in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause Celebrex (Celecoxib) to break down.
Do not keep outdated Celebrex (Celecoxib) or Celebrex (Celecoxib) no longer needed. Be sure that any discarded Celebrex (Celecoxib) is out of the reach of children.

Precautions While Using Celebrex (Celecoxib)

If you will be taking Celebrex (Celecoxib) for a long time, your doctor should check your progress at regular visits.

Stomach problems may be more likely to occur if you drink alcoholic beverages while being treated with Celebrex (Celecoxib). Therefore, do not regularly drink alcoholic beverages while taking Celebrex (Celecoxib), unless otherwise directed by your doctor.

Taking two or more of the nonsteroidal anti-inflammatory drugs together on a regular basis may increase the chance of unwanted effects. Also, taking acetaminophen, aspirin or other salicylates, or ketorolac (e.g., Toradol) regularly while you are taking a nonsteroidal anti-inflammatory drug may increase the chance of unwanted effects. The risk will depend on how much of each medicine you take every day, and on how long you take the medicines together. If your health care professional directs you to take these medicines together on a regular basis, follow his or her directions carefully. However, do not take acetaminophen or aspirin or other salicylates together with Celebrex (Celecoxib) for more than a few days, and do not take any ketorolac (e.g., Toradol) while you are taking Celebrex (Celecoxib), unless your doctor has directed you to do so and is following your progress.

Serious side effects can occur during treatment with Celebrex (Celecoxib). Sometimes serious side effects can occur without any warning. However, possible warning signs often occur, including swelling of the face, fingers, feet, and/or lower legs; severe stomach pain, black, tarry stools, and/or vomiting of blood or material that looks like coffee grounds; unusual weight gain; and/or skin rash. Stop taking Celebrex (Celecoxib) and check with your doctor immediately if you notice any of these warning signs.

Check with your doctor immediately if fever, drowsiness, itching of the skin, tiredness, nausea, or stomach pain occurs; these effects may be the first signs of liver toxicity.

Celebrex (Celecoxib)may cause a serious type of allergic reaction called anaphylaxis. Although this is rare, it may occur often in patients who are allergic to aspirin, other nonsteroidal anti-inflammatory drugs, or sulfonamide-type drugs.

Anaphylaxis requires immediate medical attention. The most serious signs of this reaction are very fast or irregular breathing, gasping for breath, wheezing, or fainting. Other signs may include changes in color of the skin of the face; very fast but irregular heartbeat or pulse; hive-like swellings on the skin; and puffiness or swellings of the eyelids or around the eyes.

If these effects occur, get emergency help at once. Ask someone to drive you to the nearest hospital emergency room. If this is not possible, do not try to drive yourself. Call an ambulance, lie down, cover yourself to keep warm, and prop your feet higher than your head. Stay in that position until help arrives.

Side Effects of Celebrex (Celecoxib)

Check with your doctor as soon as possible if you have any of the following side effects of Celebrex (Celecoxib):

More common side effects of Celebrex (Celecoxib)

Cough; fever; skin rash; sneezing; sore throat; swelling of face, fingers, feet, and/or lower legs


Less common or rare side effects of Celebrex (Celecoxib)

Bloody or black tarry stools; burning feeling in chest or stomach; chills; congestion in chest; cough; diarrhea; fatigue; fever; loss of appetite; muscle aches and pains; nausea; shortness of breath; stomach pain (severe); tenderness in stomach area; unusual weight gain; vomiting of blood or material that looks like coffee grounds; weakness


Symptoms of overdose of Celebrex (Celecoxib)

Bloody or black, tarry stools; continuing thirst; dizziness; drowsiness ; headache, severe or continuing; nausea and/or vomiting; shortness of breath; stomach pain; sudden decrease in the amount of urine; swelling of face, fingers, and/or lower legs; tightness in chest and/or wheezing; troubled breathing; unusual tiredness or weakness; vomiting of blood or material that looks like coffee grounds; weight gain


Other side effects of Celebrex (Celecoxib) may occur that usually do not need medical attention. These side effects of Celebrex (Celecoxib) may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:

More common side effects of Celebrex (Celecoxib)

Back pain; dizziness; gas; headache; heartburn ; inability to sleep; nausea ; pain or burning in throat; stomach pain; stuffy or runny nose


Less common side effects of Celebrex (Celecoxib)

Anxiety; blurred vision; buzzing or ringing noise in ears; change in sense of taste; constipation; decreased appetite; depression; difficulty swallowing; dry mouth; fast heartbeat; increased sweating; joint or muscle pain or stiffness; loss of energy or weakness; nervousness; numbness or tingling in fingers and/or toes; pain or burning in throat; pounding heartbeat; sleepiness; sudden sweating and feelings of warmth; unusual tiredness; vomiting

Precautions for using Celebrex (Celecoxib)

Allergies: Tell your doctor if you have ever had any unusual or allergic reaction to Celebrex (Celecoxib), other nonsteroidal anti-inflammatory drugs, aspirin or other salicylates, or sulfonamide-type medicines. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy: Celebrex (Celecoxib)has not been studied in pregnant women. However, there is a chance that Celebrex (Celecoxib) may cause unwanted effects on the heart or blood flow of the fetus or newborn baby if it is taken regularly during the last few months of pregnancy. Studies in animals have shown that Celebrex (Celecoxib)has caused birth defects of the ribs and sternebrae. Before taking Celebrex (Celecoxib), make sure your doctor knows if you are pregnant or if you may become pregnant.

Breast-feeding: It is not known whether Celebrex (Celecoxib)passes into breast milk. However, Celebrex (Celecoxib)may cause unwanted effects in nursing babies. It may be necessary for you to take another medicine or to stop breast-feeding during treatment. Be sure you have discussed the risks and benefits of the medicine with your doctor.

Children: Studies on Celebrex (Celecoxib) have been done only in adult patients, and there is no specific information comparing the use of Celebrex (Celecoxib)in children with use in older age groups.

Older adults: Celebrex (Celecoxib) has been tested in a limited number of elderly patients 65 years of age and older and has not been shown to cause different side effects or problems in older people than it does in younger adults. However, elderly patients may be more sensitive to the side effects of celecoxib.

Other medicines: Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking celecoxib, it is especially important that your health care professional know if you are taking any of the following:

Aspirin or Fluconazole (e.g., Diflucan): The chance of serious side effects may be increased
Lithium (e.g., Lithane): Higher blood levels of Celebrex (Celecoxib)and an increased chance of side effects may occur

Other medical problems: The presence of other medical problems may affect the use of celecoxib. Make sure you tell your doctor if you have any other medical problems, especially:

  • Alcohol abuse
  • Bleeding problems
  • Stomach ulcer or other stomach or intestinal problems
  • Tobacco use (or recent history of): The chance of side effects may be increased
  • Anemia
  • Asthma
  • Dehydration
  • Fluid retention (swelling of feet or lower legs)
  • Heart disease
  • High blood pressure
  • Kidney disease
  • Liver disease: Celebrex (Celecoxib) may make these conditions worse

For more information on side effects of Celebrex (Celecoxib), click here

 

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